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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Collagen-induced arthritis and imiquimod-induced psoriasis develop independently of interleukin-33

Fig. 4

Osteoclastogenesis and bone resorption activity in WT and IL-33-/- mice with collagen-induced arthritis (CIA). Mice as in Fig. 2 were evaluated for osteoclastogenesis (a) and bone resorption activity (b) in WT (n = 8, black bars) and IL-33-/- (n = 8, open bars) mice at day 45 after CIA induction. Bone resorption was evaluated by number of spots with resorption and percentage resorption area. Arthritic mice (c) were defined as mice with a clinical score of arthritis >0 for at least 1 day during the CIA course (IL-33-/-, n = 6; WT n = 5). Data are mean ± SEM. IL interleukin, WT wild-type

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