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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion

Fig. 6

Expression of podoplanin in PBMC alone or in co-culture. Healthy PBMC were cultured alone or in co-culture with RA synoviocytes at a 5:1 ratio for 48 h, in the presence or absence of PHA (5 μg/ml). Cells were recovered after 48 h and stained for pdpn (a and c) or CD3, CD4, IL-17 and pdpn (b). Dot plot of one experiment is represented (a and b). The percentage of pdpn + cells in the different conditions is represented (c). * p ≤ 0.05. IL interleukin, PBMC peripheral blood mononuclear cells, PHA phytohemagglutinin, pdpn podoplanin, RA rheumatoid arthritis

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