Fig. 1

Treadmill exercise repeatability (least squares mean ± standard error of the mean). A group of four animals was tested on the treadmill, recording the number of total crossings over 20 minutes (period 1 = 0–5 minutes, period 2 = 5–10 minutes, period 3 = 10–15 minutes, and period 4 = 15–20 minutes), daily from days 1 to 5, and then on days 8 and 15. The treadmill numbers of total crossings were transformed to fit a lognormal distribution. ^a,b,c Statistically significantly different inter-period statistical differences (adjusted P value = 0.002