Fig. 4

Right hind paw (RHP) withdrawal threshold evolution after induction of osteoarthritis (least squares mean ± standard error of the mean). On days 7 (adjusted P value (adj-P) = 0.07) and 14 (adj-P = 0.08), the RHP paw withdrawal threshold was increased for the rats injected with monosodium iodoacetate and punctual lidocaine (MIA-L) when compared with rats injected with MIA