Fig. 1From: Whole-genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic lupus erythematosusDifferentially expressed genes in the PBMC of SLE patients compared with normal controls. a Venn diagram shows the number of upregulated genes (left panel) and downregulated genes (right panel) in three comparisons: SLE vs. NC, SLE LN− vs. NC, and SLE LN+ vs. NC. There are 552 upregulated and 550 downregulated genes in common in all three comparisons. b Heat map shows hierarchical clustering of the commonly up- and downregulated genes in the three comparisons. NC normal controls, SLE systemic lupus erythematosus, SLE LN + SLE with lupus nephritis, SLE LN − SLE without lupus nephritisBack to article page