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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Whole-genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic lupus erythematosus

Fig. 1

Differentially expressed genes in the PBMC of SLE patients compared with normal controls. a Venn diagram shows the number of upregulated genes (left panel) and downregulated genes (right panel) in three comparisons: SLE vs. NC, SLE LN vs. NC, and SLE LN+ vs. NC. There are 552 upregulated and 550 downregulated genes in common in all three comparisons. b Heat map shows hierarchical clustering of the commonly up- and downregulated genes in the three comparisons. NC normal controls, SLE systemic lupus erythematosus, SLE LN + SLE with lupus nephritis, SLE LN SLE without lupus nephritis

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