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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Whole-genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic lupus erythematosus

Fig. 3

Gene interaction networks among the common up- and downregulated genes in the PBMC of SLE using IPA software. a Top ten pathways showing inter-relationships among 552 upregulated genes in SLE. b Top ten pathways showing inter-relationships among the 550 downregulated genes in SLE. The top ten pathways are represented by the red bar. The lines connecting the bars depict possible gene interactions in the network. The expected likelihood of the gene involved in the pathway was indicated by p value in the network

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