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Table 5 Linear mixed model of CD68+ macrophages spatial distribution within the synovial sublining: progressive decline in CD68+ macrophages with distance from the lining layer in OA and in RA

From: Inhomogeneity of immune cell composition in the synovial sublining: linear mixed modelling indicates differences in distribution and spatial decline of CD68+ macrophages in osteoarthritis and rheumatoid arthritis

Effect

Disease

Estimate

Standard error

p value

Intercept

 

5.23

1.91

0.003

ROI distance

 

−0.75

0.20

<0.0001

Disease

OA

0

  

Disease

RA

12.6

2.6

<0.0001

 Interaction: ROI and disease

OA

0

  

 Interaction: ROI and disease

RA

−0.77

0.27

0.003

  1. Estimates without standard error refer to the reference category
  2. ROI region of interest, OA osteoarthritis, RA rheumatoid arthritis