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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Bone marrow contribution to synovial hyperplasia following joint surface injury

Fig. 1

Synovial hyperplasia following joint surface injury. a Haematoxylin and eosin (H&E)-stained histological section of an injured 14-week-old mouse knee joint. Boxed area indicates the area of synovium analysed in b and c. Arrow indicates joint surface injury. P patella, F femur. Scale bar = 800 μm. b H&E-stained histological sections of uninjured (control), sham-operated and injured knee joint synovium showing hyperplasia 6 days after joint surface injury. L lining, SL sublining, C capsule, P patella, F femur. Scale bars = 100 μm. c Number of cells in the total, lining and sublining of synovium, quantified from images as in b, showing a significant increase in cellularity in both the total synovium and the synovial lining of injured but not sham-operated knees, as compared with uninjured controls. Data are expressed as the average number of cells per quantified histological section and shown as individual data points from four (uninjured and sham controls) or eight (injured) mice, with horizontal lines indicating mean values. **p < 0.01; ***p < 0.001

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