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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Bone marrow contribution to synovial hyperplasia following joint surface injury

Fig. 3

Detection of green fluorescent protein-positive (GFP+) cells in the synovium of bone marrow chimeric mice. a Representative confocal microscopic images of knee joint cryosections showing GFP+ (green) cells in the bone marrow (BM) and synovium (S) with 4′,6-diamidino-2-phenylindole (DAPI) (blue) counterstaining at multiple time points following bone marrow transplant as indicated. Scale bars = 50 μm. b Quantification of donor-derived GFP+ cells in bone marrow and synovium as percentages of total nucleated cells at the indicated time points post-transplant. Data are shown as individual data points from three mice. Horizontal lines indicate mean values. p < 0.0001 by two-way analysis of variance of bone marrow versus synovium

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