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Table 2 Abundance of leukocytes and subsets in patient whole blood

From: The type I interferon signature in leukocyte subsets from peripheral blood of patients with early arthritis: a major contribution by granulocytes

 

Based on

All patients

IFNlow

IFNhigh

Fold difference between means

Comparison of means, p value

Total leukocytes

CD45+

7191 ± 2626

7271 ± 2981

7020 ± 1814

1.04 (low > high)

0.798

Lymphocytes

CD45+, FSC/SSC

1856 ± 481 (27.8 % ± 9.7)

1955 ± 478 (29.7 % ± 10.6)

1646 ± 442 (24.0 % ± 6.1)

1.19 (low > high)

0.194

T cells

CD3+

1349 ± 365 (20.2 % ± 7.2)

1441 ± 363 (21.8 % ± 7.8)

1153 ± 304 (16.9 % ± 4.6)

1.25 (low > high)

0.066

Helper T cells

CD3+, CD4+

850 ± 228 (13.1 % ± 5.0)

899 ± 214 (13.8 % ± 5.3)

729 ± 229 (11.6 % ± 4.1)

1.23 (low > high)

0.130

Cytotoxic T cells

CD3+, CD8+

465 ± 232 (6.9 % ± 3.4)

514 ± 245 (7.6 % ± 3.7)

345 ± 148 (5.2 % ± 1.9)

1.49 (low > high)

0.187

B cells

CD19+

268 ± 125 (4.0 % ± 1.9)

284 ± 140 (4.2 % ± 2.1)

234 ± 81 (3.5 % ± 1.3)

1.21 (low > high)

0.549

Monocytes

CD14+

336 ± 127 (4.8 % ± 1.5)

353 ± 140 (5.0 % ± 1.4)

299 ± 92 (4.4 % ± 1.5)

1.18 (low > high)

0.406

PMNs

FSC/SSC

3757 ± 2715 (67.4 % ± 10.1)

3137 ± 2945 (65.3 % ± 11.0)

5075 ± 1598 (71.6 % ± 6.7)

1.61 (low < high)

0.031

  1. Abbreviations: FSC forward scatter SSC, side scatter, IFN low patients within the 95 % limits of healthy control subjects, IFN high patients with an interferon signature, PMN polymorphonuclear granulocyte
  2. Cell amounts are indicated in numbers per microliter, mean ± SD. Percentages of total leukocytes are indicated between brackets, mean ± SD