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Table 2 Abundance of leukocytes and subsets in patient whole blood

From: The type I interferon signature in leukocyte subsets from peripheral blood of patients with early arthritis: a major contribution by granulocytes

  Based on All patients IFNlow IFNhigh Fold difference between means Comparison of means, p value
Total leukocytes CD45+ 7191 ± 2626 7271 ± 2981 7020 ± 1814 1.04 (low > high) 0.798
Lymphocytes CD45+, FSC/SSC 1856 ± 481 (27.8 % ± 9.7) 1955 ± 478 (29.7 % ± 10.6) 1646 ± 442 (24.0 % ± 6.1) 1.19 (low > high) 0.194
T cells CD3+ 1349 ± 365 (20.2 % ± 7.2) 1441 ± 363 (21.8 % ± 7.8) 1153 ± 304 (16.9 % ± 4.6) 1.25 (low > high) 0.066
Helper T cells CD3+, CD4+ 850 ± 228 (13.1 % ± 5.0) 899 ± 214 (13.8 % ± 5.3) 729 ± 229 (11.6 % ± 4.1) 1.23 (low > high) 0.130
Cytotoxic T cells CD3+, CD8+ 465 ± 232 (6.9 % ± 3.4) 514 ± 245 (7.6 % ± 3.7) 345 ± 148 (5.2 % ± 1.9) 1.49 (low > high) 0.187
B cells CD19+ 268 ± 125 (4.0 % ± 1.9) 284 ± 140 (4.2 % ± 2.1) 234 ± 81 (3.5 % ± 1.3) 1.21 (low > high) 0.549
Monocytes CD14+ 336 ± 127 (4.8 % ± 1.5) 353 ± 140 (5.0 % ± 1.4) 299 ± 92 (4.4 % ± 1.5) 1.18 (low > high) 0.406
PMNs FSC/SSC 3757 ± 2715 (67.4 % ± 10.1) 3137 ± 2945 (65.3 % ± 11.0) 5075 ± 1598 (71.6 % ± 6.7) 1.61 (low < high) 0.031
  1. Abbreviations: FSC forward scatter SSC, side scatter, IFN low patients within the 95 % limits of healthy control subjects, IFN high patients with an interferon signature, PMN polymorphonuclear granulocyte
  2. Cell amounts are indicated in numbers per microliter, mean ± SD. Percentages of total leukocytes are indicated between brackets, mean ± SD