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Table 4 Type I interferon receptors IFNAR1 and IFNAR2 mRNA expression and their relationship to subset interferon scores

From: The type I interferon signature in leukocyte subsets from peripheral blood of patients with early arthritis: a major contribution by granulocytes

  Average expression Correlation with subset’s IFN score
  All patients IFNhigh patients Spearman’s r p Value
IFNAR1     
 CD4 2.473 ± 1.157 3.440 ± 1.309 0.679 0.0001
 CD8 1.723 ± 0.701 1.976 ± 0.730 0.363 0.069
 CD19 3.687 ± 1.756 3.844 ± 1.487 0.525 0.012
 CD14 0.687 ± 0.294 0.908 ± 0.354 0.371 0.068
 PMN 5.089 ± 2.243 6.529 ± 1.649 0.461 0.020
IFNAR2     
 CD4 4.544 ± 3.247 3.531 ± 1.234 0.179 0.382
 CD8 3.952 ± 2.736 2.969 ± 0.994 −0.037 0.857
 CD19 4.213 ± 2.389 2.978 ± 0.908 −0.03 0.895
 CD14 0.946 ± 0.562 0.748 ± 0.304 0.042 0.842
 PMN 5.749 ± 5.039 6.231 ± 3.340 0.507 0.010
  1. Abbreviations: IFN interferon, IFNAR interferon α/β receptor, IFN high patients with an interferon signature, PMN polymorphonuclear granulocyte