The type I interferon signature in leukocyte subsets from peripheral blood of patients with early arthritis: a major contribution by granulocytes

Table 4 Type I interferon receptors IFNAR1 and IFNAR2 mRNA expression and their relationship to subset interferon scores

	Average expression		Correlation with subset’s IFN score
	All patients	IFN^high patients	Spearman’s r	p Value
IFNAR1
CD4	2.473 ± 1.157	3.440 ± 1.309	0.679	0.0001
CD8	1.723 ± 0.701	1.976 ± 0.730	0.363	0.069
CD19	3.687 ± 1.756	3.844 ± 1.487	0.525	0.012
CD14	0.687 ± 0.294	0.908 ± 0.354	0.371	0.068
PMN	5.089 ± 2.243	6.529 ± 1.649	0.461	0.020
IFNAR2
CD4	4.544 ± 3.247	3.531 ± 1.234	0.179	0.382
CD8	3.952 ± 2.736	2.969 ± 0.994	−0.037	0.857
CD19	4.213 ± 2.389	2.978 ± 0.908	−0.03	0.895
CD14	0.946 ± 0.562	0.748 ± 0.304	0.042	0.842
PMN	5.749 ± 5.039	6.231 ± 3.340	0.507	0.010

Abbreviations: IFN interferon, IFNAR interferon α/β receptor, IFN ^high patients with an interferon signature, PMN polymorphonuclear granulocyte

ISSN: 1478-6362