Fig. 5

TNF-α-driven lung inflammation is not sufficient to induce arthritis. Ankle joint sections from 21- to 22-month-old mice that overexpress TNF-α only in the lungs under the control of the surfactant promoter and wild-type controls were H&E stained. Representative image is shown (n = 3 lung TNF and 4 WT, 100×, bar 0.2 mm). TNF-α tumor necrosis factor alpha, WT wild-type