Fig. 5From: Circadian variations in clinical symptoms and concentrations of inflammatory cytokines, melatonin, and cortisol in polymyalgia rheumatica before and during prednisolone treatment: a controlled, observational, clinical experimental studyPlasma concentrations of melatonin monitored for 24 h. Ten patients with polymyalgia rheumatica (PMR) and seven non-PMR control subjects were studied before treatment and during the 14th day of treatment with 20 mg of prednisolone. Values are mean ± SEM. Smoothed curves are included. Inverted open triangle, Variation with time in each of the groups (2P < 0.05). Open square, Difference between untreated patients and control subjects (2P < 0.05). Filled diamond, Effect of prednisolone in the patients (2P < 0.05)Back to article page