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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Suppression of the inflammatory response by disease-inducible interleukin-10 gene therapy in a three-dimensional micromass model of the human synovial membrane

Fig. 1

Immunohistochemical detection of fibroblasts and macrophages in synovial micromasses. Synovial micromasses were generated from digested synovial tissue cell suspension and cultured for 7 days. a IgG control antibody for 11-Fibrau staining. b 11-fibrau (brown) staining for synovial fibroblasts. c IgG control antibody for CD68 staining. d CD68 staining (brown) for macrophages. e Confocal fluorescent image of the micromass after transduction with lentiviral PGK-GFP. Side view with DAPI (blue) and GFP (green) staining. The micromasses used in Fig. 1a-d were derived from RA material and similar results were obtained staining OA micromass sections

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