Skip to main content

Table 1 Characteristics of the study population at baseline and follow-up

From: Impact of heart rate variability, a marker for cardiac health, on lupus disease activity

Number of patients

Baseline (n = 53)

Follow-up (n = 53)

p Values

Disease activity, median (IQR)

 SLEDAI

6 (4–9)

4 (2–6)

<0.001

 BILAG

9 (8–16)

2 (1–15)

<0.001

 PGA

1.5 (1.2–1.8)

0.9 (0.6–1.4)

<0.001

Medications, n (%)

 HCQ

35 (66)

36 (68)

1.000

 AZA

9 (17)

8 (15)

1.000

 MTX

10 (19)

15 (28)

0.360

 MMF

11 (21)

10 (19)

1.000

 CS

13 (25)

12 (23)

1.000

Parameters affecting HRV, n (%)

 Tobacco exposure

14 (26)

16 (30)

0.829

 Caffeine

27 (51)

30 (57)

0.697

 Medications ↑HRV

12 (23)

11 (21)

1.000

 Medications ↓HRV

13 (25)

11 (21)

0.816

  1. Abbreviations: SLEDAI Systemic Lupus Erythematosus Disease Activity Index, BILAG British Isles Lupus Assessment Group, PGA physician global assessment, HCQ hydroxychloroquine, AZA azathioprine, MTX methotrexate, MMF mycophenolate mofetil, CS corticosteroids
  2. P values < 0.05 are indicated in bold type