From: Reduced induction of anti-PF4/heparin antibody in RA patients after total knee arthroplasty
Total subjects | RA patients | OA patients | ||
---|---|---|---|---|
(n = 124) | (n = 26) | (n = 98) | p value | |
Gender (male/female) | 20/104 | 2/24 | 18/80 | 0.188 |
Age (years) | ||||
Mean ± SD | 73.4 ± 6.9 | 69.8 ± 8.5 | 74.3 ± 6.1 | 0.021 |
Range | 54–85 | 54–80 | 54–85 | |
BMI (kg/m2) | ||||
Mean ± SD | 26.7 ± 4.2 | 25.7 ± 4.7 | 26.9 ± 4.0 | 0.150 |
History of venous thrombosis, n (%) | 7 (5.7 %) | 3 (11.5 %) | 4 (4.1 %) | 0.143 |
Comorbidities | ||||
Hypertension | 86 (69.4 %) | 20 (76.9 %) | 66 (67.4 %) | 0.346 |
Ischemic heart disease | 6 (4.8 %) | 0 | 6 (6.1 %) | 0.196 |
Diabetes | 29 (23.4 %) | 7 (26.9 %) | 22 (22.4 %) | 0.632 |
Cerebrovascular disease | 10 (8.1 %) | 2 (7.7 %) | 8 (8.2 %) | 0.938 |
Operation time (min) | ||||
Mean ± SD | 93.7 ± 23.0 | 93.8 ± 21.1 | 93.6 ± 23.5 | 0.711 |
General anesthesia, n (%) | 124 (100 %) | 26 (100 %) | 98 (100 %) | |
Use of elastic stocking, n (%) | 124 (100 %) | 26 (100 %) | 98 (100 %) | |
Use of tourniquet, n (%) | 124 (100 %) | 26 (100 %) | 98 (100 %) | |
Use of cement, n (%) | 124 (100 %) | 26 (100 %) | 98 (100 %) | |
Prophylaxis | ||||
Edoxaban (mg/day) | 21.2 ± 7.4 | 21.3 ± 7.6 | 21.1 ± 7.4 | 0.891 |
(duration) | (11.4 ± 1.8 days) | (12.0 ± 0.6 days) | (11.3 ± 2.0 days) | 0.155 |