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Table 2 Univariate logistic regression models predicting EULAR response and DAS28 ≤ 3.2 at week 24 after rituximab

From: A combination of cellular biomarkers predicts failure to respond to rituximab in rheumatoid arthritis: a 24-week observational study

Baseline variables EULAR response DAS28 ≤ 3.2
OR (95 % CI) P value OR (95 % CI) P value
Leucocytesa 1.00 (1.00–1.00) 0. 926 1.00 (1.00–1.00) 0.892
LCa 0.91 (0.83–0.99) 0.030 0.97 (0.90–1.04) 0.420
Natural killer cellsa 0.93 (0.59–1.48) 0.766 0.85 (0.50–1.41) 0.524
B cellsa 0.48 (0.26–0.87) 0.015 0.79 (0.52–1.20) 0.274
T cellsa 0.90 (0.81–1.00) 0.050 0.98 (0.91–1.07) 0.692
CD4+ a 0.87 (0.76–0.99) 0.029 0.96 (0.86–1.08) 0.491
CD8+ a 0.94 (0.74–1.20) 0.607 1.061 (0.85–1.33) 0.640
  1. aAbsolute values, multiplied by 100. EULAR European League Against Rheumatism, DAS28 disease activity score in 28 joints, CI confidence interval, LC total lymphocyte count, OR odds ratio (indicated per 100 cells/μl increase)
  2. Significant P values are indicated in bold numbers