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Table 2 Manometric parameters at baseline and after 4-week daily administration of 20 mg buspirone

From: The 5-HT1A receptor agonist buspirone improves esophageal motor function and symptoms in systemic sclerosis: a 4-week, open-label trial

 

Baseline

After buspirone

p

Amplitude (mmHg)

16.6 ± 9.6

17.5 ± 9.6

0.163

Velocity (cm/sec)

3.7 ± 2.4

3.4 ± 1.9

0.701

Duration (sec)

2.6 ± 1.9

3.1 ± 2.3

0.668

LES resting pressure (mmHg)

7.7 ± 3.9

12.2 ± 4.6

0.00002

LES residual pressure (mmHg)

2.9 ± 1.9

3.2 ± 2.1

0.157

IRP (mmHg)

3.1 ± 2.3

3.5 ± 2.1

0.143

  1. LES lower esophageal sphincter, IRP integrated relaxation pressure
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Arthritis Research & Therapy

ISSN: 1478-6362

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