Table 1 General health characteristics of responders
All | Female | Male | P value | |
|---|---|---|---|---|
EQ-5D descriptive component scorea (median, IQR) | 0.73 (0.59, 0.85) | 0.69 (0.52,0.81) | 0.76 (0.62, 1.0) | 0.0008 |
mHAQ (median, IQR) | 0.40 (0.0, 1.0) | 0.5 (0.0, 1.0) | 0.38 (0.0, 0.9) | 0.0434 |
FACIT-Fatigue (mean, SD)a | 33.9 (12.4) | 32.0 (12.9) | 37.0 (10.8) | <0.0001 |
Insomnia (ISI) (n, %) | 0.003 | |||
No clinically significant insomnia | 244 (39.6) | 130 (33.9) | 114 (48.9) | |
Subthreshold insomnia | 227 (36.9) | 151 (39.4) | 76 (32.6) | |
Clinical insomnia (moderate severity) | 112 (18.2) | 78 (20.4) | 34 (14.6) | |
Clinical insomnia (severe) | 33 (5.4) | 24 (6.3) | 9 (3.9) | |
Anxiety (GAD–7) (n, %) | <0.0001 | |||
None (0–4) | 397 (65.0) | 220 (58.4) | 177 (75.6) | |
Mild (5–9) | 134 (21.9) | 93 (24.7) | 41 (17.5) | |
Moderate (10–14) | 49 (8.0) | 41 (10.9) | 8 (3.4) | |
Severe (15–21) | 31 (5.1) | 23 (6.1) | 8 (3.4) | |
Depression (PHQ-8) (n, %) | <0.0001 | |||
None (0–4) | 318 (52.7) | 171 (46.3) | 147 (62.8) | |
Mild (5–9) | 153 (25.4) | 93 (25.2) | 60 (25.6) | |
Moderate (10–14) | 71 (11.8) | 56 (15.2) | 15 (6.4) | |
Moderately severe (15–19) | 38 (6.3) | 30 (8.1) | 8 (3.4) | |
Severe (20–24) | 23 (3.8) | 19 (5.2) | 4 (1.7) | |
Smoking status (n, %) | <0.0001 | |||
Never smoked | 318 (49.3) | 223 (55.9) | 95 (38.6) | |
Ex-smoker | 287 (44.5) | 153 (38.4) | 134 (54.5) | |
Current smoker | 40 (6.2) | 23 (5.8) | 17 (6.9) | |
Frequency of alcohol consumption (n, %) | <0.0001 | |||
Daily or almost daily | 82 (12.6) | 26 (6.4) | 56 (22.8) | |
3–4 times a week | 82 (12.6) | 42 (10.3) | 40 (16.3) | |
1–2 times a week | 113 (17.3) | 56 (13.8) | 57 (23.2) | |
1–3 times a month | 80 (12.3) | 52 (12.8) | 28 (11.4) | |
Special occasions | 185 (28.4) | 141 (34.7) | 44 (17.9) | |
Never | 110 (16.9) | 89 (21.9) | 21 (8.5) | |
Body mass index (n, %) | 0.001 | |||
< 25 kg/m2 | 221 (33.9) | 128 (33.2) | 83 (35.0) | |
25.0–29.9 kg/m2 | 251 (40.3) | 139 (36.0) | 112 (47.3) | |
30.0–34.9 kg/m2 | 100 (16.1) | 69 (17.9) | 31 (13.1) | |
≥ 35 kg/m2 | 61 (9.8) | 50 (13.0) | 11 (4.6) | |
Count on someone to provide emotional support (n, %) | 0.009 | |||
Yes | 553 (85.2) | 355 (87.7) | 198 (81.2) | |
No | 35 (5.4) | 23 (5.7) | 12 (4.9) | |
No need | 61 (9.4) | 27 (6.7) | 34 (13.9) | |
Count on someone to provide practical support (n, %) | <0.0001 | |||
Yes | 519 (79.7) | 347 (85.5) | 172 (70.2) | |
No | 32 (4.9) | 18 (4.4) | 14 (5.7) | |
No need | 100 (15.4) | 41 (10.1) | 59 (24.1) |