Pre-symptomatic individualsa (n = 251) | RA patients (n = 192) | Controls (n = 198) | |
---|---|---|---|
Female sex, n (%) | 193 (76.9) | 144 (75.0) | 167 (84.3) |
Age, mean ± SD years | 50.5 (11.9)b | 56.5 (11.3) | 49.3 (14.8) |
Ever smoker, n (%) | 160/250 (64.0) | 129 (67.2) | 89/181 (49.2) |
HLA-DRB1 SE positivec, n (%) | 166/250 (66.4) | 122/192 (63.5) | 61/171 (35.7) |
PTPN22 1858 T carrier, n (%) | 86/250 (34.4) | 63 (32.8) | 32/173 (18.5) |