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Table 2 Potency of lesinurad (μM, mean ± SEM) against the secretory uric acid transporters OAT1 and ABCG2

From: Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney

  Secretory uric acid transporter
Compound OAT1 ABCG2
Lesinurad 3.90 ± 0.94 >100