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Table 2 Potency of lesinurad (μM, mean ± SEM) against the secretory uric acid transporters OAT1 and ABCG2

From: Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney

 

Secretory uric acid transporter

Compound

OAT1

ABCG2

Lesinurad

3.90 ± 0.94

>100

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Arthritis Research & Therapy

ISSN: 1478-6362

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