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Table 2 Crude infection rates for each medication initiation cohort

From: The risk of hospitalized infection following initiation of biologic agents versus methotrexate in the treatment of juvenile idiopathic arthritis

Medication exposure

Person-years of follow-up

Number of infections

Infection rate per 100 person-years (95 % CI)

MTX

2668.5

39

1.46 (1.07–2.00)

TNFi monotherapy

2144.0

33

1.54 (1.09–2.17)

TNFi + MTX combination

1094.5

19

1.74 (1.11–2.72)

Anakinra with or without MTX

225.9

19

8.41 (5.36–13.2)

MTX with SJIA

113.7

3

2.64 (0.85–8.18)

Etanercept

2594.0

37

1.43 (1.03–1.97)

Adalimumab

413.2

12

2.90 (1.65–5.11)

Infliximab

227.1

3

1.32 (0.43–4.10)

  1. MTX Methotrexate, TNFi Tumor necrosis factor inhibitor, SJIA Systemic juvenile idiopathic arthritis