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Table 1 Demographic and clinical characteristics of episodes of incident myocardial infarction* (MI) in allopurinol users

From: Allopurinol reduces the risk of myocardial infarction (MI) in the elderly: a study of Medicare claims

  

Incident MI during follow-up

P value

All observations

No

Yes

 

Total episodes, n

29,298

27,754

1544

 

Age (years), mean (SD)

76.6 (7.4)

76.5 (7.4)

78.1 (7.6)

<0.0001

Gender, n (%)

   

0.57

 Male

14,502 (49.5)

13,727 (49.5)

775 (50.2)

 

 Female

14,796 (50.5)

14,027 (50.5)

769 (49.8)

 

Race/ethnicity, n (%)

   

0.43

 White

23,131 (79.0)

21,922 (79.0)

1209 (78.3)

 

 Black

3583 (12.2)

3,374 (12.2)

209 (13.5)

 

 Hispanic

613 (2.1)

578 (2.1)

35 (2.3)

 

 Asian

1,281 (4.4)

1,224 (4.4)

57 (3.7)

 

 Native American

100 (0.3)

93 (0.3)

7 (0.5)

 

 Other/unknown

590 (2.0)

563 (2.0)

27 (1.7)

 

Region, n (%)

   

<0.0001

 Northeast

4736 (16.2)

4428 (16.0)

308 (20.0)

 

 Midwest

7409 (25.3)

7003 (25.2)

406 (26.3)

 

 South

11,797 (40.3)

11,220 (40.4)

577 (37.4)

 

 West

5356 (18.3)

5103 (18.4)

253 (16.4)

 

Charlson-Romano comorbidity Index Score, mean (SD)

3.65 (3.23)

3.59 (3.21)

4.79 (3.41)

<0.0001

  1. *No baseline MI within 365 days before the index date of allopurinol episode
  2. Significant differences and p values are in bold
  3. SD standard deviation