| No MI | MI | P value | |
---|---|---|---|---|
 | Not on allopurinol | On allopurinol |  | |
Number of episodes | 27,754 | 607 | 937 | Â |
Age (years), mean (SD) | 76.5 (7.4) | 77.6 (7.5) | 78.4 (7.6) | 0.046 |
Gender | Â | Â | Â | 0.13 |
 Male | 13,727 (49.5) | 290 (47.8) | 485 (51.8) |  |
 Female | 14,027 (50.5) | 317 (52.2) | 452 (48.2) |  |
Race | Â | Â | Â | 0.07 |
 White | 21,922 (79.0) | 459 (75.6) | 750 (80.0) |  |
 Black | 3374 (12.2) | 97 (16.0) | 112 (12.0) |  |
 Others | 2458 (8.8) | 51 (8.4) | 75 (8.0) |  |
Charlson-Romano comorbidity index score, mean (SD) | 3.65 (3.23) | 4.52 (3.32) | 4.96 (3.47) | 0.01 |
Comorbidity | Â | Â | Â | Â |
 Diabetes | 11076 (39.91) | 290 (47.8) | 482 (51.4) | 0.16 |
 Hypertension | 23456 (84.5) | 544 (89.6) | 811 (89.6) | 0.07 |
 CVD | 3442 (12.4) | 106 (17.5) | 184 (19.6) | 0.28 |
 PVD | 4631 (16.7) | 133 (21.9) | 247 (26.4) | 0.047 |