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Table 1 Main features of two cohorts of patients with rheumatoid arthritis

From: A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis

  Cohort I (n = 453) Cohort II (n = 1201)
Females, % 73.1 76.8
Mean age, years 65.6 ± 14.5a 46.5 ± 14.5a
Duration of follow-up, months 123.8 ± 91.5a 171.6 ± 123.6a
Extraarticular manifestations, % 22.2
Presence of joint damage, % 100
RF-positive, % 64.8 74.6
ACPA-positive, % 62.2 74.1
Number of previous DMARDs 2.2 ± 1.5a 1.7 ± 1.5a
Number of previous biologic therapies 1.8 ± 1.2a 0.6 ± 0.9a
  1. Abbreviations: RF Rheumatoid factor, DMARDs Disease-modifying antirheumatic drugs, ACPA Antibodies to citrullinated protein antigens
  2. aMean ± SD