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Table 1 Main features of two cohorts of patients with rheumatoid arthritis

From: A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis

 

Cohort I (n = 453)

Cohort II (n = 1201)

Females, %

73.1

76.8

Mean age, years

65.6 ± 14.5a

46.5 ± 14.5a

Duration of follow-up, months

123.8 ± 91.5a

171.6 ± 123.6a

Extraarticular manifestations, %

22.2

Presence of joint damage, %

100

RF-positive, %

64.8

74.6

ACPA-positive, %

62.2

74.1

Number of previous DMARDs

2.2 ± 1.5a

1.7 ± 1.5a

Number of previous biologic therapies

1.8 ± 1.2a

0.6 ± 0.9a

  1. Abbreviations: RF Rheumatoid factor, DMARDs Disease-modifying antirheumatic drugs, ACPA Antibodies to citrullinated protein antigens
  2. aMean ± SD