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Table 1 Characteristic of patients with Behçet’s disease (BD) who were enrolled in the study

From: Continuous evolution of clinical phenotype in 578 Japanese patients with Behçet’s disease: a retrospective observational study

Characteristics All (n = 578) Male (n = 247) Female (n = 331) P a
Age at onset (mean ± SD) 36.8 ± 12.4 35.2 ± 12.1 37.8 ± 12.0 0.013 b
Observation period (mean ± SD) 9.2 ± 9.2 8.2 ± 7.6 9.6 ± 8.4 0.036 b
HLA-B51, n (%) 177/352 (50.3) 88/170 (51.8) 89/182 (48.9) 0.59
Oral ulcer, n (%) 572 (99.0) 246 (99.6) 326 (98.5) 0.11
Genital ulcer, n (%) 417 (72.3) 141 (57.3) 276 (83.4) <0.0001
Eye involvement, n (%) 356 (61.6) 181 (73.3) 175 (52.9) <0.0001
Skin involvement, n (%) 513 (88.8) 212 (85.8) 301 (90.9) 0.055
Arthritis, n (%) 301 (52.1) 104 (42.1) 197 (59.5) <0.0001
Epididymitis, n (%) 14 (2.4) 14 (5.7)   
Gastrointestinal involvement, n (%) 71(12.3) 26 (10.5) 45 (13.6) 0.069
CNS involvement, n (%) 59 (10.2) 34 (13.8) 25 (7.6) 0.015
Vascular involvement, n (%) 46 (8.0) 25 (10.1) 21 (6.3) 0.097
Fulfilling ISG, n (%) 517 (89.4) 213 (86.2) 304 (91.8) 0.030
  1. aMale vs. female groups. bAnalyzed using the unpaired t test. Other variables were analyzed using the chi-square test. CNS central nervous system, ISG International Study Group criteria for BD. Significant results are highlighted in bold font