|
Characteristics
|
All (n = 578)
|
Male (n = 247)
|
Female (n = 331)
|
P
a
|
|---|
|
Age at onset (mean ± SD)
|
36.8 ± 12.4
|
35.2 ± 12.1
|
37.8 ± 12.0
|
0.013
b
|
|
Observation period (mean ± SD)
|
9.2 ± 9.2
|
8.2 ± 7.6
|
9.6 ± 8.4
|
0.036
b
|
|
HLA-B51, n (%)
|
177/352 (50.3)
|
88/170 (51.8)
|
89/182 (48.9)
|
0.59
|
|
Oral ulcer, n (%)
|
572 (99.0)
|
246 (99.6)
|
326 (98.5)
|
0.11
|
|
Genital ulcer, n (%)
|
417 (72.3)
|
141 (57.3)
|
276 (83.4)
|
<0.0001
|
|
Eye involvement, n (%)
|
356 (61.6)
|
181 (73.3)
|
175 (52.9)
|
<0.0001
|
|
Skin involvement, n (%)
|
513 (88.8)
|
212 (85.8)
|
301 (90.9)
|
0.055
|
|
Arthritis, n (%)
|
301 (52.1)
|
104 (42.1)
|
197 (59.5)
|
<0.0001
|
|
Epididymitis, n (%)
|
14 (2.4)
|
14 (5.7)
| | |
|
Gastrointestinal involvement, n (%)
|
71(12.3)
|
26 (10.5)
|
45 (13.6)
|
0.069
|
|
CNS involvement, n (%)
|
59 (10.2)
|
34 (13.8)
|
25 (7.6)
|
0.015
|
|
Vascular involvement, n (%)
|
46 (8.0)
|
25 (10.1)
|
21 (6.3)
|
0.097
|
|
Fulfilling ISG, n (%)
|
517 (89.4)
|
213 (86.2)
|
304 (91.8)
|
0.030
|
-
aMale vs. female groups. bAnalyzed using the unpaired t test. Other variables were analyzed using the chi-square test. CNS central nervous system, ISG International Study Group criteria for BD. Significant results are highlighted in bold font
