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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: A novel DNA/histone H4 peptide complex detects autoantibodies in systemic lupus erythematosus sera

Fig. 3

Specificity of anti-DNA antibodies by inhibition ELISA. SLE serum A (a) or serum B (b) were incubated with 1:4 dilutions of the PK/H4 complex, plasmid DNA (PK) or histone 5 (H4) peptide and then transferred to PK/H4 complex-coated plates. Results are expressed as percent inhibition of the binding observed in the absence of inhibitors [100 – (OD of inhibitor/OD of buffer) × 100]. A higher inhibition is obtained with PK/H4 complexes in the case of serum A, while in serum B complex or plasmid DNA pre-incubation results in identical inhibition. No inhibition is obtained with H4 peptide

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