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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: A novel DNA/histone H4 peptide complex detects autoantibodies in systemic lupus erythematosus sera

Fig. 4

Diagnostic properties of PK/H4 complexes: correlations with Aeskulisa anti-dsDNA assay, ECLAM, anti-C1q, and C3. The amount of IgG specific for the PK/H4 complex are correlated with the level of anti-dsDNA antibodies detected by Aeskulisa (a), with the ECLAM score (b; r = 0.4094, p < 0.0001), and with anti-C1q autoantibodies titers (c; r = 0.3106; p = 0.0176), and inversely correlated with complement C3 levels (d; r = –0.4196; p < 0.0001). C1q complement component 1q, ECLAM European Consensus Lupus Activity Measurement, H4 histone 4, PK plasmid DNA

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