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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Glucocorticoid-induced leucine zipper (GILZ) is involved in glucocorticoid-induced and mineralocorticoid-induced leptin production by osteoarthritis synovial fibroblasts

Fig. 5

Glucocorticoid-induced leucine zipper (GILZ) expression under prednisolone and aldosterone stimulation was dose dependent. Human osteoarthritis (OA) synovial fibroblasts were stimulated for 5 days with increasing concentrations of a glucocorticoid (prednisolone) or mineralocorticoid (aldosterone). GILZ messenger RNA (mRNA) expression was measured by RT-qPCR. Graphs represent mean +/- SD (n = 4 patients). Significance was set at p < 0.05. b*Significantly different from a; c not significantly different from a

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