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Table 1 Baseline characteristics of individuals with affected relatives with systemic sclerosis and the general population

From: Familial risk of systemic sclerosis and co-aggregation of autoimmune diseases in affected families

Variables

≥1 Affected relatives

General population

P value

No.

3801

23,658,577

 

Male gender (n (%))

2037 (53.59)

11,732,064 (49.59)

<0.001

Age (years) (mean ± SD)

46.6 ± 16.2

37.5 ± 20.4

<0.001

Systemic sclerosis (n (%))

3 (0.08)

1891 (0.008)

<0.001

Place of residence (n (%))

 Urban

2421 (63.69)

13,935,055 (58.90)

<0.001

 Suburban

991 (26.07)

6,581,657 (27.82)

 

 Rural

267 (7.02)

2,186,647 (9.24)

 

 Unknown

122 (3.21)

955,218 (4.04)

 

Income levels (n (%))

 Quintile 1

594 (15.63)

4,077,139 (17.23)

<0.001

 Quintile 2

529 (13.92)

3,334,917 (14.10)

 

 Quintile 3

881 (23.18)

6,296,926 (26.62)

 

 Quintile 4

830 (21.84)

4,547,059 (19.22)

 

 Quintile 5

847 (22.28)

4,437,878 (18.76)

 

 Unknown

120 (3.16)

964,658 (4.08)

 

Occupation (n (%))

 Dependents of the insured individuals

1185 (31.18)

9,209,334 (38.93)

<0.001

 Civil servants, teachers, military personnel and veterans

195 (5.13)

984,451 (4.16)

 

 Non-manual workers and professionals

1426 (3752)

6,357,208 (26.87)

 

 Manual workers

631 (16.60)

4,885,084 (20.65)

 

 Other

364 (9.58)

2,222,500 (9.39)