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Table 1 Baseline characteristics of individuals with affected relatives with systemic sclerosis and the general population

From: Familial risk of systemic sclerosis and co-aggregation of autoimmune diseases in affected families

Variables ≥1 Affected relatives General population P value
No. 3801 23,658,577  
Male gender (n (%)) 2037 (53.59) 11,732,064 (49.59) <0.001
Age (years) (mean ± SD) 46.6 ± 16.2 37.5 ± 20.4 <0.001
Systemic sclerosis (n (%)) 3 (0.08) 1891 (0.008) <0.001
Place of residence (n (%))
 Urban 2421 (63.69) 13,935,055 (58.90) <0.001
 Suburban 991 (26.07) 6,581,657 (27.82)  
 Rural 267 (7.02) 2,186,647 (9.24)  
 Unknown 122 (3.21) 955,218 (4.04)  
Income levels (n (%))
 Quintile 1 594 (15.63) 4,077,139 (17.23) <0.001
 Quintile 2 529 (13.92) 3,334,917 (14.10)  
 Quintile 3 881 (23.18) 6,296,926 (26.62)  
 Quintile 4 830 (21.84) 4,547,059 (19.22)  
 Quintile 5 847 (22.28) 4,437,878 (18.76)  
 Unknown 120 (3.16) 964,658 (4.08)  
Occupation (n (%))
 Dependents of the insured individuals 1185 (31.18) 9,209,334 (38.93) <0.001
 Civil servants, teachers, military personnel and veterans 195 (5.13) 984,451 (4.16)  
 Non-manual workers and professionals 1426 (3752) 6,357,208 (26.87)  
 Manual workers 631 (16.60) 4,885,084 (20.65)  
 Other 364 (9.58) 2,222,500 (9.39)