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Table 2 Relative risks of systemic sclerosis and other autoimmune diseases for individuals with affected first-degree relatives

From: Familial risk of systemic sclerosis and co-aggregation of autoimmune diseases in affected families

Autoimmune diseases With affected relatives General population Relative risk (95 % CI)a
No. of cases Prevalence (%) No. of cases Prevalence (%)  
Systemic sclerosis 3 0.08 1891 0.008 13.23 (3.11–56.33)
Rheumatoid arthritis 11 0.29 37,482 0.16 2.64 (1.46–4.75)
Systemic lupus erythematosus 20 0.53 18,915 0.08 6.51 (4.05–10.46)
Sjögren’s syndrome 4 0.11 12,754 0.05 2.77 (1.04–7.35)
Idiopathic inflammatory myositis 2 0.05 1808 0.01 8.05 (2.03–31.92)
Type I diabetes mellitus 5 0.13 10,281 0.04 2.51 (0.90–7.07)
Multiple sclerosis 1 0.03 1252 0.01 5.16 (0.73–3665)
Psoriasis 47 1.24 196,333 0.83 1.52 (1.15–2.01)
  1. a Adjusted for age, gender, place of residence, quintiles of income levels, occupations, and family size