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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease

Fig. 1

Interference in toll-like receptor 4 (TLR4) signaling blocks IL-6, TNFα, IL-1β and IL-8 production by monocytes stimulated by synovial fluid from patients with rheumatoid arthritis (RASF). TLR4 signaling was blocked with anti-human TLR4 monoclonal antibody, NI-0101. Representative data shown for monocytes obtained from one of seven patients with rheumatoid arthritis (RA). Data are presented as mean +/- SEM. The Mann-Whitney U test was performed to identify differences among groups: **p < 0.01, ***p < 0.001

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Arthritis Research & Therapy

ISSN: 1478-6362

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