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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease

Fig. 3

Expression of anti-citrullinated protein antibodies (ACPA) and ligands of toll-like receptor 4 in samples of synovial fluid (SF) from patients with rheumatoid arthritis (RA) and correlation between these and NI-0101 response. a Expression of ACPA, HMGB1 and S100A8/A9 in SF from subjects without RA (non-RA SF) (n = 4 samples) and patients with RA (RASF) (n = 40 samples). b Correlation between ACPA, HMGB1 or S100A8/A9 and NI-0101 response. RASF samples were classified as NI-0101 non-responders (NR) or NI-0101 responders (R) according to Fig. 2. The Mann-Whitney U test was performed to test for differences among groups; *p < 0.05, **p < 0.01

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