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Table 4 Association of IPFP hypointense signals with WOMAC measures and increases in WOMAC measures over 2.6 years

From: Hypointense signals in the infrapatellar fat pad assessed by magnetic resonance imaging are associated with knee symptoms and structure in older adults: a cohort study

  Multivariablea Multivariableb Multivariablec
OR (95 % CI) OR (95 % CI) OR (95 % CI)
Baseline WOMAC measures
 Total knee pain 1.27 (1.03, 1.56) 1.07 (0.85, 1.35) 1.15 (0.93, 1.43)
  Pain on flat surface 1.22 (0.97, 1.55) 1.02 (0.79, 1.33) 1.13 (0.88, 1.44)
  Pain on stairs 1.26 (1.02, 1.55) 1.05 (0.84, 1.32) 1.14 (0.92, 1.42)
  Pain in bed 1.47 (1.16, 1.85) 1.42 (1.10, 1.82) 1.42 (1.12, 1.79)
  Pain when sitting 1.29 (1.02, 1.64) 1.25 (0.96, 1.62) 1.24 (0.97, 1.58)
  Pain when standing 1.22 (0.96, 1.55) 1.10 (0.85, 1.43) 1.12 (0.87, 1.43)
Increases in WOMAC measures
 Total knee pain 1.36 (1.05, 1.76) 1.32 (0.99, 1.74) 1.30 (1.00, 1.69)
  Pain on flat surface 1.52 (1.08, 2.14) 1.22 (0.83, 1.79) 1.33 (0.94, 1.89)
  Pain on stairs 1.51 (1.14, 2.01) 1.34 (0.98, 1.82) 1.42 (1.06, 1.89)
  Pain in bed 1.18 (0.85, 1.63) 1.04 (0.73, 1.49) 1.14 (0.82, 1.58)
  Pain when sitting 1.25 (0.88, 1.78) 1.14 (0.77, 1.67) 1.20 (0.84, 1.71)
  Pain when standing 1.44 (1.02, 2.03) 1.22 (0.84, 1.78) 1.38 (0.98, 1.97)
  1. Dependent variables: baseline WOMAC measures or increases in WOMAC measures (yes vs. no); independent variables: IPFP hypointense signals (per grade)
  2. IPFP infrapatellar fat pat, WOMAC Western Ontario and McMasters osteoarthritis index
  3. aAdjusted for age, sex, BMI, and radiographic osteoarthritis
  4. bFurther adjustment for cartilage defects
  5. cFurther adjustment for bone marrow lesions but not for cartilage defects