Table 1 Intersect of significantly increased IgG-autoantibodies in patients with established RA (cohort A) and early RA (cohort B)

DCTN1

Dynactin 1

1639

0.026

1.5

14

0.001

1.5

19

GNPTG

N-acetylglucosamine-1-phosphate transferase

84572

0.021

1.2

17

0.001

1.3

13

HNRNPA1

Heterogeneous nuclear ribonucleoprotein A1-like 2

144983

0.020

1.3

22

0.000

1.3

34

ITFG3

Integrin alpha FG-GAP repeat containing 3

83986

0.048

1.1

19

0.014

1.1

23

APOA4

Apolipoprotein A-IV

337

0.025

1.1

35

0.001

1.2

11

CCDC136

Coiled-coil domain containing 136

64753

0.039

2.2

14

0.031

1.7

2

CKAP4

Cytoskeleton-associated protein 4

10970

0.027

1.2

22

0.000

1.3

28

CLCN2

Chloride channel 2

1181

0.037

1.3

19

0.016

1.2

10

DMTF1

Cyclin D binding myb-like transcription factor 1

9988

0.047

1.3

22

0.022

1.3

11

FAM59B

Family with sequence similarity 59. member B

150946

0.047

1.9

18

0.000

1.5

15

IGFBP2

Insulin-like growth factor binding protein

3485

0.015

1.2

19

0.000

1.5

13

TMCO7

Transmembrane and coiled-coil domains 7

79613

0.009

1.1

21

0.000

1.5

20

USP48

Ubiquitin specific peptidase 48

84196

0.001

2.7

18

0.034

1.7

11

VIM

Vimentin

7431

0.022

1.3

19

0.000

1.7

38

ZFAND2B

Zinc finger. AN1-type domain 2B

130617

0.034

1.2

18

0.002

1.3

22

ATP6V1A

ATPase. H+ transporting. lysosomal 70 kDa. V1 subunit A

523

0.048

1.2

21

0.042

1.3

11

GSN

Gelsolin

2934

0.008

1.4

26

0.001

1.4

12

GSPT2

G1 to S phase transition 2

23708

0.045

1.2

14

0.043

1.3

8

HSBP1

Heat shock factor binding protein 1

3281

0.021

1.2

25

0.002

1.3

19

NONO

Non-POU domain containing. octamer-binding

4841

0.010

1.4

21

0.016

1.3

17

PRAP1

Proline-rich acidic protein 1

118471

0.030

1.3

14

0.035

1.6

9

YES1

YES proto-oncogene 1. Src family tyrosine kinase

6714

0.032

1.1

28

0.010

1.2

13

SSB

Sjogren syndrome antigen B (autoantigen La)

6741

0.009

1.4

15

0.042

1.1

17