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Table 3 Intersect of significantly increased IgG autoantibodies in patients with RA (cohorts A, B, and C)

From: Sequential high-content profiling of the IgG-autoantibody repertoire reveals novel antigens in rheumatoid arthritis

Antigen

Cohort A

Cohort B

Cohort C

symbol

Name

Gene ID

P

FC

S

P

FC

S

P

FC

S

GNPTG

N-acetylglucosamine-1-phosphate transferase

84572

0.021

1.2

17

0.001

1.3

13

0.04

1.1

10

HNRNPA1

Heterogeneous nuclear ribonucleoprotein A1-like 2

144983

0.020

1.3

22

0.000

1.3

34

0.001

1.1

24

IGFBP2

Insulin-like growth factor binding protein 2

3485

0.01

1.2

19

0.000

1.5

13

0.03

1.1

15

  1. Cohort A: patients with established rheumatoid arthritis (RA) (n = 72). cohort B: early RA (n = 116). cohort C: early seronegative RA (n = 184). P is p value for fold change (FC) and sensitivity (S) at 90 % specificity compared to matched healthy controls, according to the Mann-Whitney test
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Arthritis Research & Therapy

ISSN: 1478-6362

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