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Table 3 Intersect of significantly increased IgG autoantibodies in patients with RA (cohorts A, B, and C)

From: Sequential high-content profiling of the IgG-autoantibody repertoire reveals novel antigens in rheumatoid arthritis

Antigen Cohort A Cohort B Cohort C
symbol Name Gene ID P FC S P FC S P FC S
GNPTG N-acetylglucosamine-1-phosphate transferase 84572 0.021 1.2 17 0.001 1.3 13 0.04 1.1 10
HNRNPA1 Heterogeneous nuclear ribonucleoprotein A1-like 2 144983 0.020 1.3 22 0.000 1.3 34 0.001 1.1 24
IGFBP2 Insulin-like growth factor binding protein 2 3485 0.01 1.2 19 0.000 1.5 13 0.03 1.1 15
  1. Cohort A: patients with established rheumatoid arthritis (RA) (n = 72). cohort B: early RA (n = 116). cohort C: early seronegative RA (n = 184). P is p value for fold change (FC) and sensitivity (S) at 90 % specificity compared to matched healthy controls, according to the Mann-Whitney test