Table 2 Changes in MRI parameters

Lateral compartment

–4.1 ± 3.1

–4.4 ± 3.0

0.814

 Condyle

–3.0 ± 3.1

–4.1 ± 3.7

0.144

 Plateau

–5.8 ± 4.7

–4.8 ± 3.5

0.182

Medial compartment

–6.3 ± 3.2

–8.1 ± 4.2

0.018

 Condyle

–5.5 ± 3.9

–7.7 ± 4.7

0.008

 Plateau

–7.6 ± 4.0

–8.6 ± 4.8

0.276

Synovial membrane thickness^b (mm)

0.13 ± 0.25

0.14 ± 0.24

0.948

Synovial fluid volume (ml)

–2.6 ± 14.5

–2.0 ± 11.8

0.776

BML score^b

1.1 ± 1.7

0.8 ± 1.7

0.322

ATP population

Chondroitin sulfate

Celecoxib

p value^a

Chondroitin sulfate

Celecoxib

p value^a

(n = 57)^c

(n = 63)

(n = 57)^c

(n = 63)

 Lateral compartment

–3.4 ± 2.7

–3.3 ± 2.5

0.932

–4.6 ± 3.0

–4.4 ± 2.8

0.753

  Condyle

–2.5 ± 3.2

–3.0 ± 3.0

0.234

–3.4 ± 3.0

–4.2 ± 3.6

0.316

  Plateau

–4.6 ± 3.5

–3.8 ± 3.1

0.194

–6.3 ± 4.6

–4.8 ± 3.5

0.081

 Medial compartment

–4.5 ± 2.6

–5.6 ± 3.0

0.049

–6.6 ± 3.3

–8.4 ± 4.2

0.021

  Condyle

–3.8 ± 3.2

–5.0 ± 3.8

0.100

–5.7 ± 4.0

–8.1 ± 4.7

0.010

  Plateau

–5.5 ± 3.0

–6.6 ± 3.8

0.155

–8.0 ± 4.2

–9.0 ± 4.8

0.334

Synovial membrane thickness^b (mm)

0.03 ± 0.18

0.06 ± 0.18

0.579

0.15 ± 0.26

0.15 ± 0.24

0.731

Synovial fluid volume (ml)

–5.5 ± 12.6

–1.8 ± 9.2

0.326

–3.9 ± 15.4

–2.1 ± 12.2

0.945

BML score^b

0.7 ± 1.4

0.3 ± 1.2

0.051

1.1 ± 1.7

0.8 ± 1.7

0.322