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Table 3 Changes at 24 months in synovial membrane thickness and cartilage volume

From: Chondroitin sulfate efficacy versus celecoxib on knee osteoarthritis structural changes using magnetic resonance imaging: a 2-year multicentre exploratory study

  

Decreasea

Increasea

 

Chondroitin sulfate

(n = 26)b

Celecoxib

(n = 24)b

p valuec

Chondroitin sulfate

(n = 12)

Celecoxib

(n = 8)

p valuec

Chondroitin sulfate

(n = 12)

Celecoxib

(n = 14)

p valuec

Medial suprapatellar bursa

 Synovial membrane thickness loss (mm)

–0.66 ± 22.72

+17.96 ± 33.73

0.076

–0.23 ± 0.27

–0.14 ± 0.21

0.446

+0.13 ± 0.09

+0.25 ± 0.17

0.030

Medial compartment

 Cartilage volume loss (%)

–6.8 ± 3.5

–9.4 ± 4.7

0.045

–7.5 ± 3.7

–11.3 ± 3.5

0.036

–6.4 ± 3.4

–7.8 ± 4.8

0.404

  1. Data are mean ± standard deviation
  2. aData from patients who presented a decrease or an increase in synovial membrane thickness at 24 months
  3. bSynovial membrane thickness measurement is reliant on the presence of synovial fluid to localise the membrane; absence of synovial fluid accounts for missing values
  4. cStudent’s t test or Wilcoxon Mann–Whitney test, bold indicates statistical significance