Fig. 4
Per-cycle analysis of pre-treatment, post-treatment and retreatment counts of CD4+ T cells. In each cycle only patients for whom data were available were included. Each dot represents one patient and lines represent the mean with SD. The limits of the reference range are presented (between 700 and 1100/mm 3). CD4+ cell counts were compared between the three points, i.e. before treatment, 3 or 6 months post treatment and before retreatment for each cycle usingWilcoxon’s matched-pairs signed rank test: ****p < 0.0001, ***p < 0.001, **p < 0.005, *p < 0.05; NS not significant