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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Elevated expression of miR-142-3p is related to the pro-inflammatory function of monocyte-derived dendritic cells in SLE

Fig. 1

Pro-inflammatory function of moDCs in SLE. The supernatants derived from culture medium of moDCs from negative controls (n = 5) and patients with SLE (n = 5) in the presence of LPS (1 μg/ml) for 24 hours was assessed using cytometric bead array including CCL2 (a, *P < 0.001), CCL5 (b, *P = 0.002), IL-6 (c, *P = 0.002), CXCL8 (d, no significant difference) and TNF-α (e, no significant difference). Percentage of CD4+ T cells attracted by supernatants of culture medium, supernatants of moDCs in NC, and supernatants of moDCs in SLE group (f, # P < 0.05 versus supernatants of culture medium and supernatants of moDCs in NC, *P < 0.05 versus supernatants of culture medium). Data were shown as mean ± SD. CCL C-C motif ligand, CXCL C-X-C motif ligand, IL interleukin, moDCs monocyte-derived DCs, NC negative controls, SLE systemic lupus erythematosus, TNF-α tumor necrosis factor alpha

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