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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Elevated expression of miR-142-3p is related to the pro-inflammatory function of monocyte-derived dendritic cells in SLE

Fig. 6

Elevated expression level of miR-142-3p affected moDCs-CD4+ T cells interaction. a Percentage of CD4+ T cells attracted by supernatants of moDCs in NC or empty lentiviral vector (VEC) or lentivirus (LV) group measured by a Transwell chamber. # P < 0.05 versus NC and VEC. b The percentage of CD4+CD25+Foxp3+ Tregs among CD4+ T cells co-cultured with moDCs was assessed using flow cytometry and data of one representative experiment (c) out of three independent experiments was shown. Foxp3+ cells were gated from CD4+CD25+ T cells. Data were shown as means ± SD of three independent experiments. # P < 0.05 versus NC and VEC. d and e The level of exocrine secretion of IL-17 (# P < 0.001 versus NC and VEC) and IL-10 (# P < 0.05 versus NC and VEC) in the supernatants derived from co-culture medium of CD4+T cells- moDCs. N = 3 in each group. Data were shown as means ± SD. IL interleukin

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