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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Circulating exosomes from patients with systemic lupus erythematosus induce a proinflammatory immune response

Fig. 6

Correlation between SLE disease activity and cytokine production by exosomes. a Serum exosome levels correlated significantly with SLE disease activity index 2K (SLEDAI) in nine patients with SLE. Production of IFN-α (b), TNF-α (c), IL-1β (d), and IL-6 (e) by the healthy PBMCs after stimulation with SLE exosomes (n = 8) correlated with SLEDAI. P values were generated by using Spearman correlation. IFN interferon, IL interleukin, TNF tumor necrosis factor

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