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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: p53 predominantly regulates IL-6 production and suppresses synovial inflammation in fibroblast-like synoviocytes and adjuvant-induced arthritis

Fig. 3

Inflammatory cytokines inhibited expression of p53 in FLS in a dose-dependent manner. a p53 expression was reduced in FLS after the stimulation with TNF-α and IL-1β at 0.1, 1.0, and 10 ng/ml, respectively. b IL-1β and IL-17 synergistically inhibited expression of p53 and its related proteins p21 and p27, but not Bax. IL interleukin, TNF tumor necrosis factor

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Arthritis Research & Therapy

ISSN: 1478-6362

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