Fig. 2

Haemolytic activity of plasma samples collected from patients with systemic sclerosis. Left column shows classical pathway haemolytic activity of 1% plasma, and right column shows alternative pathway activity of 5% plasma. Value of 1 on y-axis corresponds to the readout of normal human plasma (NHP). Results are means ± standard deviation derived from two independent experiments, and statistical significance is set at *p < 0.05 according to Mann-Whitney U test.Abbreviations: SRC Scleroderma renal crisis, PAH Pulmonary arterial hypertension, lcSSc Limited cutaneous systemic sclerosis, dcSSc Diffuse cutaneous systemic sclerosis.  Graphs comparing the patients with vs. without ulcers, pitting scars and telangiectasias are not shown, because the differences between groups did not reach statistical significance