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Table 2 Correlations between complement biomarkers C4d, C3bBbP and terminal complement complex in plasma samples from patients with autoimmune diseases

From: Analysis of complement biomarkers in systemic sclerosis indicates a distinct pattern in scleroderma renal crisis

Disease C4d-TCC correlation C3bBbP-TCC correlation C4d-C3bBbP correlation
Spearman’s r p value Spearman’s r p value Spearman’s r p value
SSc (n = 122) −0.06 0.47 0.47 <0.0001a 0.099 0.27
RA (n = 81) 0.12 0.29 0.41 0.0001a 0.26 0.018b
PsoA (n = 22) 0.035 0.88 0.52 0.013b 0.086 0.70
AS (n = 20) −0.33 0.15 0.52 0.019b −0.20 0.40
  1. Abbreviations: AS Ankylosing spondylitis, PsoA Psoriatic arthritis, RA Rheumatoid arthritis, SSc Systemic sclerosis, TCC Terminal complement complex
  2. a p <0.001
  3. b p < 0.05