Fig. 1
Schematic representation of immunoglobulin G. Indicated is what is generally considered as the Fc and Fab or F(ab’)2 portion. The glycans of both Fc and Fab consist of the same building blocks, although the most abundant glycans may differ vastly in their appearance. This figure was originally published in Bondt et al, Immunoglobulin G (IgG) Fab glycosylation analysis using a new mass spectrometric high-throughput profiling method reveals pregnancy-associated changes. Mol Cell Proteomics. 2014; 13:3029–3039. © the American Society for Biochemistry and Molecular Biology, and slightly adapted for the current manuscript