Table 4 Associations between individual HLA-DRB1 haplotype and achieving good/moderate EULAR response, in overall RA, as well as in ACPA-positive RA and ACPA-negative RA

PRAA

Reference

Reference

Reference

DFRE

1.60 (0.51–5.03)

1.60 (0.48–5.34)

NA

GYRQ

0.59 (0.29–1.19)

0.64 (0.28–1.47)

0.18 (0.03–1.28)

LFEA

0.23 (0.04–1.55)

NA

NA

LFRA

0.89 (0.51–1.56)

0.93 (0.49–1.79)

0.33 (0.06–1.88)

PRRA

0.89 (0.20–3.94)

2.15 (0.23–20.28)

NA

SGRA

0.72 (0.26–1.96)

0.81 (0.27–2.47)

0.28 (0.01–5.30)

SGRL

1.00 (0.41–2.43)

1.23 (0.37–4.10)

0.14 (0.02–0.95)

SSEA

0.92 (0.45–1.86)

1.31 (0.53–3.28)

0.12 (0.02–0.73)

SSKA

2.49 (0.29–21.30)

NA

0.12 (0.01–2.59)

SSKR

0.99 (0.47–2.10)

1.23 (0.51–2.99)

0.04 (0.00–0.39)

SSRA

1.98 (0.78–5.00)

2.43 (0.81–7.32)

0.55 (0.06–5.03)

SSRE

1.59 (0.32–7.82)

2.58 (0.30–22.14)

0.10 (0.00–2.41)

VFRA

0.52 (0.21–1.24)

0.60 (0.22–1.63)

0.17 (0.01–2.84)

VHEA

1.14 (0.11–12.24)

1.58 (0.14–17.89)

NA

VHKA

0.78 (0.46–1.32)

1.08 (0.59–1.97)

0.16 (0.03–0.93)

VHRA

1.10 (0.62–1.97)

1.20 (0.62–2.33)

0.93 (0.11–8.00)

VHRE

1.03 (0.31–3.43)

2.11 (0.43–10.35)

0.03 (0.00–0.55)

PAA

Reference

Reference

Reference

DRE

1.59 (0.51–5.01)

1.56 (0.47–5.20)

NA

GRQ

0.59 (0.29–1.19)

0.63 (0.27–1.45)

0.19 (0.03–1.33)

LEA

0.23 (0.03–1.50)

NA

NA

LRA

0.89 (0.51–1.55)

0.93 (0.49–1.77)

0.34 (0.06–1.92)

PRA

0.90 (0.20–3.98)

2.11 (0.22–19.84)

NA

SEA

0.95 (0.47–1.91)

1.36 (0.55–3.39)

0.13 (0.02–0.75)

SKA

2.62 (0.31–22.35)

NA

0.13 (0.01–2.73)

SKR

1.01 (0.48–2.13)

1.26 (0.52–3.05)

0.05 (0.00–0.43)

SRA

1.34 (0.64–2.79)

1.51 (0.65–3.52)

0.48 (0.06–3.63)

SRE

1.52 (0.31–7.42)

2.47 (0.29–21.15)

0.10 (0.00–2.51)

SRL

0.94 (0.39–2.27)

1.20 (0.36–3.98)

0.13 (0.02–0.92)

VEA

1.15 (0.11–12.39)

1.56 (0.14–17.60)

NA

VKA

0.77 (0.46–1.30)

1.06 (0.58–1.94)

0.15 (0.03–0.91)

VRA

0.95 (0.55–1.64)

1.04 (0.55–1.94)

0.64 (0.09–4.31)

VRE

1.03 (0.31–3.44)

2.08 (0.42–10.27)

0.04 (0.00–0.66)