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Table 2 Comparison of patients with and without renal atrophy 24 months after the start of glucocorticoid therapy

From: Factors related to renal cortical atrophy development after glucocorticoid therapy in IgG4-related kidney disease: a retrospective multicenter study

 

Atrophy (+) (n = 11)

Atrophy (-) (n = 12)

P value

Age (years)

62.6 ± 10.7

61.6 ± 13.5

0.951

Gender (male, %)

72.7

75.0

1.000

Allergy (%)

54.5

75.0

0.400

Number of extra-renal organs

2.8 ± 1.0

3.3 ± 1.6

0.423

IgG4 (mg/dL)

909 ± 587

1216 ± 454

0.065

IgG (mg/dL)

3001 ± 1505

3040 ± 1015

0.424

IgE (IU/mL)

587 ± 254

284 ± 263

0.008

CH50 (IU/L)

31.0 ± 20.5

34.9 ± 14.8

0.498

CRP (mg/dL)

0.31 ± 0.38

0.19 ± 0.32

0.251

Cr (mg/dL)

1.23 ± 0.59

0.80 ± 0.20

0.052

eGFR (mL/min/1.73 m2)

68.9 ± 30.1

93.5 ± 14.1

0.036

Initial dose of PSL (mg/kg/day)

0.52 ± 0.18

0.62 ± 0.16

0.124

Other immunosuppressant drugs (%)

9.1

33.3

0.317

ARB (%)

27.3

16.7

0.640

Relapse (%)

18.2

50.0

0.193

Diabetes mellitus (%)

36.4

25.0

0.667

Hypertension (%)

27.3

16.7

0.640

Ischemic heart disease (%)

0

8.3

1.000

Smoking habit (%)

50.0

54.5

1.000

  1. Conversion factor for serum creatinine at diagnosis (Cr) mg/dL to μmol/L, ×88.4. ARB angiotensin II receptor blocker, CRP serum C-reactive protein at diagnosis, eGFR estimated glomerular filtration rate at diagnosis, IgG serum immunoglobulin G at diagnosis, IgG4 serum immunoglobulin G4 at diagnosis, IgE serum immunoglobulin E at diagnosis, PSL prednisolone