Skip to main content

Table 3 Odds ratio for risk of renal atrophy development 24 months after the start of therapy: unadjusted and age-adjusted, sex-adjusted, serum IgG4 level-adjusted logistic regression

From: Factors related to renal cortical atrophy development after glucocorticoid therapy in IgG4-related kidney disease: a retrospective multicenter study

Variable

Unadjusted

Age-adjusted, sex-adjusted, serum IgG4 level-adjusted

OR

95% CI

P value

OR

95% CI

P value

Age (per year)

1.007

0.939 to 1.080

0.844

1.023

0.948 to 1.104

0.553

Male sex

0.889

0.138 to 5.723

0.901

2.045

0.228 to 18.311

0.522

Allergy

0.400

0.068 to 2.337

0.309

0.327

0.040 to 2.674

0.297

Serum IgG4 concentration at baseline (per 10 mg/dL)

0.988

0.970 to 1.005

0.175

0.983

0.963 to 1.005

0.125

Serum IgG concentration at baseline (per 10 mg/dL)

1.000

0.993 to 1.006

0.938

1.006

0.995 to 1.017

0.270

Serum IgE concentration at baseline (per 10 IU/mL)

1.056

1.004 to 1.111

0.035

1.090

1.013 to 1.174

0.022

Serum C3 concentration at baseline (per mg/dL)

1.001

0.977 to 1.025

0.957

0.995

0.967 to 1.024

0.718

Serum C4 concentration at baseline (per mg/dL)

0.987

0.896 to 1.088

0.795

0.982

0.881 to 1.094

0.740

Serum CH50 titer at baseline (per IU/L)

0.987

0.940 to 1.036

0.585

0.980

0.928 to 1.034

0.452

Serum CRP concentration at baseline (per mg/dL)

2.776

0.208 to 37.079

0.440

6.149

0.273 to 138.380

0.253

eGFR at baseline (per 10 mL/min/1.73 m2)

0.600

0.365 to 0.987

0.043

0.520

0.273 to 0.993

0.048

Number of organs involved

0.715

0.634 to 1.436

0.350

0.793

0.330 to 1.910

0.606

Initial PSL dose (per mg/kg/day)

0.022

0.000 to 6.131

0.184

0.050

0.000 to 54.982

0.402

Other immunosuppressant drugs

0.200

0.019 to 2.162

0.185

0.140

0.010 to 2.041

0.150

ARB

1.875

0.250 to 14.082

0.541

1.008

0.088 to 11.573

0.995

Diabetes mellitus

1.714

0.285 to 10.383

0.556

1.813

0.191 to 17.236

0.605

Hypertension

1.875

0.250 to 14.082

0.541

0.908

0.070 to 11.815

0.941

Smoking habit

0.833

0.150 to 4.636

0.835

0.652

0.091 to 4.655

0.669

  1. Conversion factor for creatinine (Cr): mg/dL to μmol/L, ×88.4. ARB angiotensin II receptor blocker, CI confidence interval, CRP C-reactive protein, eGFR estimated glomerular filtration rate, OR odds ratio, IgG immunoglobulin G, IgG4 immunoglobulin G4, IgE immunoglobulin E, PSL prednisolone
Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us