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Table 1 Odds ratios for RF and anti-CCP2 autoantibodies in association with smoking in a population-based non-RA cohort

From: Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study

 

RFanti-CCP2 (n = 8836)

RF+anti-CCP2 (n = 572)

RFanti-CCP2+ (n = 125)

RF+anti-CCP2+ (n = 42)

Smoking ever (%)

3117 (35.3)

178 (31.1)

39 (31.2)

22 (52.4)

Smoking never (%)

5719 (64.7)

394 (68.9)

86 (68.8)

20 (47.6)

Odds ratio (95% CI)

1 (reference)

0.94 (0.75–1.18)

0.97 (0.6–1.58)

2.95 (1.32–6.58)*

p value

0.23

0.48

<0.001*

  1. *Significant values (p < 0.05)
  2. anti-CCP2 anti-cyclic citrullinated peptide antibodies, CI confidence interval, RA rheumatoid arthritis, RF rheumatoid factor